Excited to share our latest publication in ACS Chemical Biology!
- aaronrobart0
- 2 hours ago
- 1 min read
We used cryo-EM and biochemical probing to reveal how the 10–23 DNAzyme folds into its active structure and responds to magnesium ions. These findings provide new insight into one of the most widely studied catalytic DNAs.
Congratulations to co-first authors Evan Cramer and Holly Shultz on this accomplishment, and thank you to the UVa Molecular Electron Microscopy Core for their outstanding support of this work!
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